THE POWER OF TURMERIC CURCUMIN

Curcuma longa (turmeric), a spice and superfood, has been used throughout history in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin diferuloyl-methane (the primary constituent and the one responsible for its vibrant yellow color), demethoxycurcumin, bisdemethoxy-curcumin, volatile oils (tumerone, atlantone, and zingiberone), sugars, proteins, and resins.

The Power of Turmeric Curcumin While curcumin has been attributed by numerous pharmacological activities, including antioxidant and antimicrobial properties, based on early research conducted with cell cultures and animal models, pilot and clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, chronic anterior uveitis, and certain types of cancer. Numerous clinical trials are currently in progress which, over the next few years, will provide an even deeper understanding of the therapeutic potential of curcumin.

Because of curcumin's rapid plasma clearance and conjugation, its therapeutic usefulness has been somewhat limited, leading researchers to investigate the benefits of complexing curcumin with other substances to increase systemic bioavailability. Numerous in-progress clinical trials should provide an even deeper understanding of the mechanisms and therapeutic potential of curcumin. (Alter Med Rev 2009:14(2):141-153)

Piperine, a known bioavailability enhancer, is the major active component of black pepper and is associated with an increase of 2000% in the bioavailability of curcumin.

Anti-inflammatory Mechanisms of Curcumin

Research shows curcumin is a highly pleiotropic molecule capable of interacting with numerous molecular targets involved in inflammation. Curcumin modulates the inflammatory response by down-regulating the activity of cyclooxygenase-2 (COX-2), lipoxygenase, and inducible nitric oxide synthase (iNOS) enzymes; inhibiting the production of the inflammatory cytokines tumor necrosis factor-alpha (TNF-a), interleukin (IL) -1, -2, -6, -8, and -12, monocyte chemoattractant protein (MCP), and migration inhibitory protein; and down-regulates mitogen-activated and Janus kinases.

''Low-Grade Inflammation has been identified as a factor in the development of many chronic diseases and conditions'

Why Fusionary Formulas?

We offer safe, effective, and non-addictive pain relief in a natural form

Orthopedic surgeons around the US recommend our formulas to patients for pain

We use medical-grade ingredients to formulate our supplements

Our products are made in the USA in a GMP-compliant physician-owned factory.

All of our ingredients are lab tested for authenticity and safety

Here’s what makes us different

Many turmeric curcumin supplements just give you regular turmeric powder or they give you all three curcuminoids found in Turmeric. The problem with this? Regular turmeric powder isn’t the most effective way to reduce inflammation. Fusionary Formulas believes in using the most potent high quality ingredients,. We believe that investing in the highest quality 98% potency curcumin extract helps drive down inflammation and pain.